Charles V, Holy Roman Emperor elect, leaves Spain to attend to his dominions in northern Europe. Before his departure, he appoints Adrian of Utrecht as Regent of Castile.
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Citation: Editors, Litencyc. "Charles V leaves Spain for northern Europe". The Literary Encyclopedia. First published 01 November 2010 [https://www.litencyc.com/php/stopics.php?rec=true&UID=14261, accessed 29 March 2024.]